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The Benefits of Lactobacillus Acidophilus DDS1 Probiotic

Nutritionist Kay Ali with Beauty Pie Supergut probiotic supplement

Let’s take a deep dive into the benefits of Lactobacillus Acidophilus DDS1 probiotic.

Unfortunately, not all bacteria sold on the market actually meet the classification of a true probiotic. You can read more about it in my guide for shopping for the best probiotic here. In short, three key factors determine a fantastic probiotic. Survivability, meaningful dose and robust scientific evidence that the strain provides a benefits to humans. Lactobacillus Acidophilus DDS1 meets all three, which is why I love it. Let’s take a closer look.

Survivability & Adherence

In order to benefit from your friendly bacteria it’s got to remain alive when it reaches the intestines. This means it has to withstand the low pH environment in the stomach and duodenum. On its journey there it has to bypass very acidic chemicals such as Hydrochloric Acid (HCL), pepsin, bile salts and pancreatin. In vitro evidence demonstrates that Lactobacillus Acidophilus DDS1 is one of the most resistant friendly bacteria available. It withstood low pH conditions and pepsin. It even survived against bile salts and pancreatin at physiological concentrations found in the small intestine.

What’s more is, the same study found that Lactobacillus Acidophilus DDS1 exhibited strong adherence potential to representative human intestinal cell lines. In English? It may actually colonise your own gut flora. This is incredible. Most probiotics work via a transitory mechanism, where they improve the environment of the luminal gastrointestinal tract as they pass through. Very few have the ability to actually adhere to the luminal wall and colonise our own microbiome. Yet, researchers back in the 1980s were able to mimic the in vitro results in animal studies suggesting Lactobacillus Acidophilus DDS1 has strong adherence capabilities.[1], [2]


Beauty Pie Supergut probiotic formulated by Nutritionist Kay Ali


It gets better. A human trial with 10 subjects were administered two billion Colony Forming Units (CFU) of Lactobacillus Acidophilus DDS1 for three weeks.[3] Stool concentrations of Lactobacillus Acidophilus DDS1 were determined before and after the three-week intervention period. The 10 subjects experienced a mean 100-fold increase in fecal concentrations of L. acidophilus following three weeks of daily supplementation. This outcome suggests spectacular survivability of Lactobacillus Acidophilus DDS1 following oral administration in humans. And after only 3 weeks of use!

So, what exactly does Lactobacillus Acidophilus DDS1 do?

Lactobacillus Acidophilus DDS1 has over 30 years of clinical research spanning over 200 studies. Here are just a few of my favourite proven benefits. Click on each to learn more.


[1] Pollmann DS, Danielson DM, Wren WB, et al. J Anim Sci 1980;51:638–44. [2] Pollmann DS, Danielson DM, Wren WB, et al. J Anim Sci 1980;51:629–37. [3] Peterson L. Studies on DDS-acidophilus at VA hospital, Minneapolis. 1998. [4] Gerasimov SV, Vasjuta VV, Myhovych OO et al. Am J Clin Dermatol 2010;11:351–61. [5] Gerasimov SV, Ivantsiv VA, Bobryk LM, et al. Eur J Clin Nutr 2016;70:463–9. [6] Pakdaman MN, Udani JK, Molina JP, et al. Nutr J 2016;15:56. [7] Nagala R, Routray C. US Gastroenterol Hepatol Rev 2011;7:36-7. [8] Martoni, CJ, Srivastava, S, Leyer, GJ, Nutrients 2020 12, 363 [9] Senhert KW. Effect of DDS-acidophilus, A case study. 1989.

Disclaimer: The statements made in this blog post are for educational and entertainment purposes only. They are not intended to diagnose or treat any individual or condition. If you are concerned about your health please consult your licensed medical doctor before changing your diet or taking supplements. This website uses affiliate links, which means the author may earn from products and services recommended although it should be noted that this is not at an additional cost to the consumer.


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